The Difference of Anti-HBs Levels in Babies Vaccinated with Hepatitis B Vaccine Between at 2, 4, 6 Months with 2, 3, 4 Months Schedule in Denpasar

Background: Hepatitis B virus is one of the causes major health problem throughout world. vaccine way to control HBV infections effectively. The prevalence HB infection shows a decreased effectivity vaccination. Objective: To discover differences in anti-HBs levels between two schedules vaccination recommended by Indonesian Pediatric Society (at 2, 4, 6 months vs 3, 4 age). Methods: This was an observational study on healthy babies comparing effect treatment groups, each consisting 30 subjects. Subjects were chosen stratified random sampling. Blood samples withdrawn three after subjects received their last dose vaccination, either schedule (Group 1) or 2). We used independent t-test assess mean groups. A p-value of<0.05 considered statistically significant. Results: found significant difference Group 1 and 2 (820.06 mIU/ml 540.54 mIU/ml, respectively, p=0.002). Conclusion: Both produced protective completed schedule. level group higher compared 2.